Whole-cell currents of GIRK1/2, the calculated surface density and Iβγ/Itotal in Xenopus oocytes.

Data are shown as mean±SEM (except Iβγ/Itotal), number of cells is shown in parentheses. Data for each entry were collected from at least 2 independent experiments. The Table summarizes separate sets of experiments: those where Ibasal, Ievoked and Itotal were measured (in each oocyte); and those where Gβγ was coexpressed and Iβγ was measured. In addition, in Set 2, Ibasal was measured in each experiment in a separate group of oocytes not injected with Gβγ RNA. For the low density group in oocytes, there was ~30% difference (p = 0.017) for Ibasal between the two sets of experiments, probably because of variability among oocyte batches. In intermediate and high density groups Ibasal was not different (p>0.4) for both sets of experiments.Whole-cell currents of GIRK1/2, the calculated surface density and Iβγ/Itotal in Xenopus oocytes.