PDAC-SMI and co-culture dataset

This dataset includes two parts: (1) The spatial molecular imaging (SMI) data for 13 PDAC tumors that either received neoadjuvant chemo/radiation therapy or were treatment naive. Raw data files (images, cell segmentation, expression data, metadata) are included in the SMI_raw folder. The count matrix, metadata, and cell type annotations are included in the PDAC_raw_meta_data.h5ad file. (2) The processed single nucleus RNA-seq data for CAF–malignant co-culture tumoroids, stored in a Seurat object file.