Characterization of a novel breast cancer cell line derived from a metastatic bone lesion of a breast cancer patient [Genotype]. Homo sapiens

As organ-specific models of breast cancer bone metastasis do not exist, we established a novel breast cancer line was established from the ER-/PR-/HER2- bone metastasis from a breast cancer patient. This cell line was characterized and compared to the primary tumour and/or normal mammary epithelial cells with regards to phenotypes (i.e. marker expression), gene expression and copy number variation. Overall design: Genomic DNA was isolated from the P7731 cell line the primary tumour and hybridised using the SNP arrays Illumina HumanCNV370-Duov1 DNA Analysis BeadChip (HumanCNV370v1) Please note that the complete processed data is provided as sample supplementary text file.