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Metabolic drivers of ovarian cancer tumor growth. Homo sapiens

NIAID Data Ecosystem2026-03-09 收录

癌细胞重编程

卵巢癌分子机制

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA307288 数据链接链接失效反馈

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资源简介：

Effect of SHMT1 knockdown on ovarian cancer tumor growth was analyzed Overall design: PEO4 cells expressing non-silencing shRNA or SHMT1 shRNAs were analyzed for gene expression alterations

应用场景：

创建时间：

2015-12-30

癌细胞重编程

线粒体功能障碍

The conserved B-subunit of succinate dehydrogenase (SDH) participates in the TCA cycle and mitochondrial electron transport. The Arg230His mutation in SDHB causes heritable pheochromocytoma/paragangl

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Gene expression profile of ascites cell samples from patients with advanced ovarian cancer

卵巢癌分子机制

基因表达谱分析

We present evidence for an autocrine cytokine network in human ovarian cancer that has paracrine actions on the tumour microenvironment. In experiments using bioinformatics analysis of large gene expr

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Hypoxia responsive genes in human Burkitt’s lymphoma cell line, P493-6.

缺氧诱导基因调控

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Activation of glycolytic genes by HIF-1 is considered critical for metabolic adaptation to hypoxia. We found that HIF-1 also actively suppresses glucose metabolism through the tricarboxylic acid cycl

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Depletion of Nrf2 in pancreatic cancer cells shifts arginine metabolism into the phosphocreatine energy system. Depletion of Nrf2 in pancreatic cancer cells shifts arginine metabolism into the phosphocreatine energy system

癌细胞重编程

癌症靶向治疗

Depletion of Nrf2 leads to an increase in cellular ROS, reduced glutathione and thiols, and profound reprogramming of metabolism. Unbiased transcriptome analyses show that key enzymes of glycolysis, p

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Effect of oncogene-induced transformation on metabolic enzyme core set

癌细胞重编程

癌基因功能分析

The expression levels of metabolic enzymes were estimated by MRM analysis with internal standard recombinant proteins. The analysis is performed in human diploid fibroblasts, TIG-3 cells and their der

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Metabolic drivers of ovarian cancer tumor growth. Homo sapiens

资源简介：

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