Characterization of the genes that were regulated by infection with Malassezia furfur

In the present study, we investigated the pathogenicity of infection with Malassezia furfur using Caenorhabditis elegans as a model animal. The lifespan of the adult C. elegans infeted with Malassezia furfur was significantly longer than that of uninfected animals (control). Transcriptional profiling comparing infected- and uninfected animals suggested that genes related to the innate immunity were upregulated by infection with Malassezia furfur. Transcriptional profiling of three-day-old worms that were infected or uninfected with Malassezia furfur for six hours, by deep sequencing, using Illumina HiSeq.