Genetic Determinants of Transcriptional Variation in Primary Human Monocytes Across Multiple Contexts

Monocytes undergo global gene expression changes upon stimulation, thus a significant proportion of eQTL are specific to activation state. Here we systematically explore determinants of gene and transcript expression in monocytes from 185 individuals in the untreated state and post-exposure to IFNγ or lipopolysaccharide (LPS).EGA study EGAS00001007111