TCR repertoire sequencing related to "Unique roles of coreceptor-bound LCK in helper and cytotoxic T cells"

This archive contains datasets needed for recapitulating the analysis of TCR repertoires for the manuscript <em>“Unique roles of coreceptor-bound LCK in helper and cytotoxic T cells”</em> by Horkova et al., 2022. The code for the analysis can be found on GitHub: https://github.com/Lab-of-Adaptive-Immunity/lck-tcrseq. Raw data are deposited in the SRA (https://www.ncbi.nlm.nih.gov/bioproject/PRJNA872031). The Zenodo archive contains the following files, which are needed to run the analysis script: merged outputs from MiXCR <code>merged_TCR_repertoires.csv</code> metadata file <code>metadata_Lck.csv</code> TRA and TRB repertoires prepared for processing with the Immunarch package <code>immdata_tra.rds</code>, <code>immdata_trb.rds</code>