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A Double-blind, Double-dummy, Randomized, Parallel Groups Study to Assess the Efficacy, Safety and Tolerability of Switching Patients With Early Parkinson's Disease (PD) From Pramipexole IR to Pramipexole ER or Pramipexole IR

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DataCite Commons2025-05-01 更新2026-05-07 收录
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https://search.vivli.org/doiLanding/studies/00003496/isLanding
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资源简介:
The objectives of this trial conducted in early Parkinson's disease (PD) patients are: - To assess if patients with early Parkinson's disease (PD) can be successfully switched (overnight switching) from Pramipexole (PPX) Immediate Release (IR) to Pramipexole Extended Release (ER). A successful switch at a specific visit is defined as no worsening of the Unified Parkinsons Disease Rating Scale (UPDRS) parts II+III score by more than 15% from baseline and no drug-related adverse events leading to withdrawal; - To establish if this successful switch can be obtained with or without dose-adaptation; - To provide information about the conversion ratio (mg:mg) from Pramipexole IR to Pramipexole ER.
提供机构:
Vivli
创建时间:
2019-04-12
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