Effects of BRCA2 cis-regulation in normal breast and cancer risk amongst BRCA2 mutation carriers

ChEBI2012-02-01 更新2026-07-21 收录

BRCA2基因

乳腺癌遗传

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-32259 数据链接链接失效反馈

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Effects of BRCA2 cis-regulation in normal breast and cancer risk amongst BRCA2 mutation carriers

创建时间：

2012-02-01

MOESM1 of No association of TP53 codon 72 and intron 3 16-bp duplication polymorphisms with breast cancer risk in Chinese Han women: new evidence from a population-based caseâcontrol investigation

乳腺癌遗传

TP53基因

Additional file 1: Table S1. Distributions of the genotype frequencies of codon 72 and intron 3 16-bp duplication polymorphisms in breast cancer patients with different clinicopathological features.

NIAID Data Ecosystem120

Risk of BC associated with the combination of 3 susceptible SNPs.

乳腺癌遗传

易感基因分析

†Adjusted for age, BMI, age at menarche, age at first full-term pregnancy, menopause status and family history of cancer in first-degree relatives. ‡Rs3218035 and rs3218042 can be tags for each other

NIAID Data Ecosystem50

Germline BRCA2 mutations drive prostate cancers with distinct evolutionary trajectories. Homo sapiens

前列腺癌分子机制

BRCA2基因

Germline mutations in the BRCA2 tumour suppressor are associated with both an increased lifetime risk of developing prostate cancer (PCa) and increased risk of aggressive disease. To understand this a

NIAID Data Ecosystem30

Genome-wide mapping of DNA-methylation in hTert-HME1 cell line treated with control or BRCA2 siRNAs and grown with or without EGF (epithelial growth factor). Genome-wide mapping of DNA-methylation in hTert-HME1 cell line treated with control or BRCA2 siRNAs and grown with or without EGF (epithelial growth factor)

BRCA2基因

肿瘤抑制基因

Individuals with a single functional copy of the BRCA2 tumor suppressor have elevated risks for breast, ovarian, and other solid tumor malignancies. The exact mechanisms of carcinogenesis due to BRCA2

NIAID Data Ecosystem50

DataSheet1_Association Between the TP53 Polymorphisms and Breast Cancer Risk: An Updated Meta-Analysis.PDF

乳腺癌遗传

基因多态性分析

Background: The relationship of TP53 codons 72, IVS3 16 bp, and IVS6+62A > G polymorphisms with breast cancer (BC) risk has been analyzed in seventeen published meta-analyses. However, the credibility

NIAID Data Ecosystem40

Effects of BRCA2 cis-regulation in normal breast and cancer risk amongst BRCA2 mutation carriers

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