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Yap Promotes Outbound Noncanonical Wnt Signaling from Cardiomyocytes to Fibroblast to Enhance Neonatal Heart Regeneration

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NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE179355
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We used Bulk RNA sequencing to determine the global transcriptional effects of Wls cKO in cardiomyocytes on mouse injury response after MI. Cardiomyocytes and Non-Cardiomyocytes were collected from each mice. Each mice received three consecutive doses of TAM from P1-P3, and mice underwent MI at P2. Samples were collected 2 weeks are surgery. 3 Hearts were collected from each experimental condition.
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2021-10-19
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