CUT & RUN for P63, Gata3, Jun in murine keratinocytes and Tcf1 and Jun in murine CD8 Naive T-cells across two age stages, young (2 months) and aged (20-24 months).

We performed CUT&RUN and assessed cumulative TF binding signal shifts between age-opening and closing regions in young (2 months) and aged (20-24 months) murine samples. Overall design: TF Binding signal shifts between age-closing and age-opening regions were assessed. Differentially Accessible Regions (DARs) were derived from the same cell types, namely keratinocytes and CD8 Naive T-cells from young (2 months) vs aged (20-24 months) murine sample groups.