Consecutive Gold(I)-Catalyzed Cyclization Reactions of <i>o</i>‑(Buta-1,3-diyn-1-yl-)-Substituted <i>N</i>‑Aryl Ureas: A One-Pot Synthesis of Pyrimido[1,6‑<i>a</i>]indol-1(2<i>H</i>)‑ones and Related Systems
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Treatment of readily available o-(buta-1,3-diyn-1-yl-)-substituted N-aryl ureas such as 1 with the Au(I)-catalyst 11 affords, via a twofold cyclization process, the isomeric pyrimido[1,6-a]indol-1(2H)-one 3 in good yield.
创建时间:
2013-06-07



