Nasopharyngeal microbiome signature in COVID-19 positive patients

Several factors can influence SARS-CoV-2 onset and the severity of its complications.Recent evidences showed the possible relationship between gut, lung, nasopharyngeal or oral microbiome and COVID-19.The aim of this study was to verify if the nasopharyngeal microbiome could influence both the development of COVID-19 and the severity of symptoms.Hypervariable V1-V2-V3 regions of the bacterial 16S rRNA in nasopharyngeal swabs from SARS-CoV-2 infected patients (n=18) and control (CO) individuals (n=12) was analyzed by next generation sequencing (NGS)