QuantSeq libraries to study TDP-43 dependent alternative polyadenylation
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QuantSeq libraries to study TDP-43 dependent alternative polyadenylation
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2019-02-25
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Additional file 2: of QAPA: a new method for the systematic analysis of alternative polyadenylation from RNA-seq data
Neuronal differentiation APA. This tab-delimited file contains the QAPA-estimated PAU and Sailfish TPM values of each 3ⲠUTR isoform for samples from the Hubbard et al. [29] RNA-seq dataset. (TXT 62
NIAID Data Ecosystem50
Additional file 10: of Alternative polyadenylation produces multiple 3’ untranslated regions of odorant receptor mRNAs in mouse olfactory sensory neurons
Table S4. Alternative 3′ ends for pilot genes annotated from RNA-Seq data and RL-PAT experimental validation. The 3′ end positions and the relative abundances of the resulting 3’UTR isoforms were obta
Figshare2019-07-13 更新30
Additional file 5 of Benchmarking sequencing methods and tools that facilitate the study of alternative polyadenylation
Additional file 5: DaPars2.PAS.sites. DaPars2 PAS sites with PAU > 5% (BED format).
Figshare2021-10-15 更新30
The 3' end processing factor PCF11 regulates gene expression based on gene size and intronic polyadenylation. The 3' end processing factor PCF11 regulates gene expression based on gene size and intronic polyadenylation
Genes with different sizes have distinct expression patterns and functions. Here we show that the 3' end processing PCF11 modulates gene expression according to gene size. Gene density and polyA site
NIAID Data Ecosystem40
TDP-43 dysfunction restricts dendritic complexity by inhibiting CREB activation and altering gene expression. TDP-43 dysfunction restricts dendritic complexity by inhibiting CREB activation and altering gene expression
Identified TDP-43 targets in rat cortical neurons, many related to the CREB pathway Overall design: First application of TRIBE in mammalian system, used human ADAR2 catalytic domain for the experiment
NIAID Data Ecosystem30
