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2022-07-21
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Computational Reconstruction of NFκB Pathway Interaction Mechanisms during Prostate Cancer
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Tiwari2019 - Mathematical model of NFKB regulatory module with TNF and ROS
It is a dynamic model containing elements of two different model as one. It contains the impact of TNF on SOD and impact of ROS on A20 behavior.
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Radulescu2008_NFkB_hierarchy_M_24_45_62
NFkB model M(24,45,62) This is a model of NFkB pathway functioning from hierarchy of models of decreasing complexity, created to demonstrate application of model reduction methods proposed
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Identification of New IκBα Complexes by an Iterative Experimental and Mathematical Modeling Approach
The transcription factor nuclear factor kappa-B (NFκB) is a key regulator of pro-inflammatory and pro-proliferative processes. Accordingly, uncontrolled NFκB activity may contribute to the development
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Negative feedback systems for modelling NF-κB transcription factor oscillatory activity
Low-dimensional negative feedback systems (NFSs) were developed within a signal flow model to describe the oscillatory activities of NF-κB caused by interactions with its inhibitor IκBα. The NFSs were
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