Crystal structure of CYP3A4 in complex with an inhibitor
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Crystal structure of CYP3A4 in complex with an inhibitor Descriptor: (8R)-3,3-difluoro-8-[4-fluoro-3-(pyridin-3-yl)phenyl]-8-(4-methoxy-3-methylphenyl)-2,3,4,8-tetrahydroimidazo[1,5-a]pyrimidin-6-amine, Cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE Authors: Branden, G, Sjogren, T, Xue, Y. Deposit date: 2013-12-10 Release date: 2014-08-13 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.95 Å) Cite: Structure-based ligand design to overcome CYP inhibition in drug discovery projects. Drug Discov Today, 19, 2014
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2013-12-10
