Pathogenic germline mitochondrial genome (mtDNA) mutations cause debilitating and often fatal diseases in children. Mitochondrial replacement therapies (MRT) circumventing mother to child transmission
We analyzed mitochondrial DNA methylation levels of both the CpG and the non-CpG sites in the nucleus accumbens (NAcc) and the prefrontal cortex (PFC) with whole mitochondrial genome bisulfite sequenc
