Formal Substitution of Bromocyclopropanes with Nitrogen Nucleophiles
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A highly chemo- and diastereoselective protocol toward amino-substituted donor–acceptor cyclopropanes via the formal nucleophilic displacement in bromocyclopropanes is described. A wide range of N-nucleophiles, including carboxamides, sulfonamides, azoles, and anilines, can be efficiently employed in this transformation, providing expeditious access to stereochemically defined and densely functionalized cyclopropylamine derivatives.
创建时间：
2013-08-02
