Total RNA for deep sequencing was isolated by using TRIzol reagent (Invitrogen, Carlsbad, CA, USA) according to the manufacturer's protocol, with some modifications. Each sample added 300 ul TRIzol (I
The potency and indiscriminate nature of formaldehyde reactivity upon biological molecules make it a universal stressor. However, some organisms such as Methylorubrum extorquens possess means to rapid