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Ligand-Free Copper-Catalyzed Regioselective C-2 Arylation of Imidazo[2,1-b]thiazoles

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Figshare2016-02-22 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Ligand_Free_Copper_Catalyzed_Regioselective_C_2_Arylation_of_Imidazo_2_1_i_b_i_thiazoles/2605801
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An effective, regioselective C-2 arylation of imidazo[2,1-b]thiazoles catalyzed by Cu(I) has been developed. This arylation proceeded smoothly without promotion of the ligands, and various functional (22 samples) groups were well tolerated. Preliminary mechanistic studies of this arylation are also reported.
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2016-02-22
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