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Crystal structure of Plasmodium falciparum HPPK-DHPS wild type with SDX-DHP

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Protein Data Bank Japan2023-11-22 更新2026-03-21 收录
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Crystal structure of Plasmodium falciparum HPPK-DHPS wild type with SDX-DHP Descriptor: 2-AMINO-6-HYDROXYMETHYL-7,8-DIHYDRO-3H-PTERIDIN-4-ONE, 4-[(2-azanyl-4-oxidanylidene-7,8-dihydro-3~{H}-pteridin-6-yl)methylamino]-~{N}-(5,6-dimethoxypyrimidin-4-yl)benzenesulfonamide, 7,8-dihydro-6-hydroxymethylpterin pyrophosphokinase-dihydropteroate synthase, ... Authors: Chitnumsub, P, Jaruwat, A, Yuthavong, Y. Deposit date: 2019-04-21 Release date: 2020-02-12 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.5 Å) Cite: The structure of Plasmodium falciparum hydroxymethyldihydropterin pyrophosphokinase-dihydropteroate synthase reveals the basis of sulfa resistance. Febs J., 287, 2020
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2019-04-21
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