Crystal structure of human Prolyl-tRNA synthetase (PRS) in complex with inhibitor

Crystal structure of human Prolyl-tRNA synthetase (PRS) in complex with inhibitor Descriptor: 3-[(cyclohexanecarbonyl)amino]-N-(2,3-dihydro-1H-inden-2-yl)pyrazine-2-carboxamide, Bifunctional glutamate/proline--tRNA ligase, PROLINE, ... Authors: Okada, K, Skene, R.J. Deposit date: 2017-03-24 Release date: 2017-05-31 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.36 Å) Cite: Discovery of a novel prolyl-tRNA synthetase inhibitor and elucidation of its binding mode to the ATP site in complex with l-proline. Biochem. Biophys. Res. Commun., 488, 2017