Crystal structure of human KDM5B in complex with compound 34g
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Crystal structure of human KDM5B in complex with compound 34g Descriptor: 1,2-ETHANEDIOL, 8-[4-(1-cyclopentylpiperidin-4-yl)pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one, DIMETHYL SULFOXIDE, ... Authors: Le Bihan, Y.V, Velupillai, S, van Montfort, R.L.M. Deposit date: 2018-07-23 Release date: 2019-06-12 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.14 Å) Cite: C8-substituted pyrido[3,4-d]pyrimidin-4(3H)-ones: Studies towards the identification of potent, cell penetrant Jumonji C domain containing histone lysine demethylase 4 subfamily (KDM4) inhibitors, compound profiling in cell-based target engagement assays. Eur.J.Med.Chem., 177, 2019
创建时间：
2018-07-23
