Crystal structure of EGFR double mutant (T790M/L858R) in complex with compound 6.
收藏Protein Data Bank Japan2024-11-13 更新2026-03-28 收录
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Crystal structure of EGFR double mutant (T790M/L858R) in complex with compound 6. Descriptor: 2-[2-(3-methoxyphenyl)pyrimidin-4-yl]-1'-prop-2-enoyl-spiro[5,6-dihydro-1~{H}-pyrrolo[3,2-c]pyridine-7,4'-piperidine]-4-one, Epidermal growth factor receptor Authors: Collie, G.W. Deposit date: 2021-06-22 Release date: 2021-10-20 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.56 Å) Cite: Discovery and optimization of covalent EGFR T790M/L858R mutant inhibitors". Bioorg.Med.Chem.Lett., 2021
创建时间：
2021-06-22
