Transcription profiling by array of mouse colon mucosal tissues isolated every 4 hours within a 24-hour period to study genes involved in circadian regulation

In mammals circadian clocks are present not only in the hypothalamus but also in all peripheral organs where they rhytmically control tissue specific biological processes. Here, the transcriptome of the mouse colon mucosa was analyzed around the clock to identify genes whose gene expression is under circadian regulation.