Crystal structure of the Keap1 Kelch domain in complex with the small molecule UCAB#985 at 1.65 Angstrom resolution

Crystal structure of the Keap1 Kelch domain in complex with the small molecule UCAB#985 at 1.65 Angstrom resolution Descriptor: (3~{S})-3-[7-[2-(cycloheptylamino)-2-oxidanylidene-ethoxy]naphthalen-2-yl]-3-(6-methyl-1,3-benzodioxol-5-yl)propanoic acid, CHLORIDE ION, DIMETHYL SULFOXIDE, ... Authors: Narayanan, D, Bach, A, Gajhede, M. Deposit date: 2025-01-06 Release date: 2025-09-03 Last modified: 2025-10-08 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Fragment-Based Drug Discovery of Novel High-affinity, Selective, and Anti-inflammatory Inhibitors of the Keap1-Nrf2 Protein-Protein Interaction. Angew.Chem.Int.Ed.Engl., 64, 2025