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The methyl-CpG-binding protein 2 inhibits cGAS-associated signaling

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NIAID Data Ecosystem2026-05-10 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP557008
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We analyzed the impact of dsDNA stimulation on transcriptomics and retrotranscriptomics profiles in murine cell lines (Mouse Embryonic Fribroblasts and RAW264.7). Overall design: WT-RAW264.7 and WT-MEF were transfected (or not: Mock) with dsDNA prior to RNA or DNA extraction respectively. WT and Mecp2 KO RAW264.7 cells were subjected to RNA extraction. All experiemtns were performed in triplicates.
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2026-02-07
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