Model design choices impact biological insight: Unpacking the broad landscape of spatial-temporal model development decisions: SYSTEM REPRESENTATION

Data and results for SYSTEM REPRESENTATION simulations.

Simulations of cancerous cells in colony and tissue contexts using rectangular or hexagonal geometry in 2D and 3D. Each condition is run for 15 days (21600 ticks) with 50 replicates (random seeds 0 - 49). Cancerous cells (max_height x 1.5, meta_pref x 1.5, migra_threshold x 0.5) are introduced to the center of the environment after a 1 day delay. Snapshots are taken every 0.5 days (720 ticks).

The data folder contains .tar.xz compressed replicate sets. The results folder contains .csv.xz files of compressed parsed data.

Simulations are labelled as: [context]_[dimension]_[geometry]

- [context]
- C = colony context, cancerous cells only
- CH = tissue context, cancerous cells and healthy cells
- [dimension]
- 2D = 2D simulation (radius = 34, margin = 6, height = 1)
- 3D = 3D simulation (radius = 26, margin = 6, height = 51)
- [geometry]
- rect = rectangular geometry
- hex = hexagonal geometry

本数据集包含 SYSTEM REPRESENTATION 模拟的数据和结果。
模拟了癌变细胞在群落和组织环境中的二维和三维矩形或六边形几何形态下的生长过程。每个条件模拟持续15天（21600个时间步），进行50次重复实验（随机种子从0至49）。在延迟1天后，将癌变细胞（最大高度为max_height x 1.5，元偏好值为meta_pref x 1.5，迁移阈值migra_threshold x 0.5）引入到环境中心。每隔0.5天（720个时间步）进行一次快照。
数据文件夹包含.tar.xz压缩的重复实验集。结果文件夹包含.csv.xz压缩的解析数据。
模拟标签形式为：[环境]_[维度]_[几何形状]

- [环境]
- C = 群落环境，仅包含癌变细胞
- CH = 组织环境，包含癌变细胞和健康细胞
- [维度]
- 2D = 二维模拟（半径 = 34，边距 = 6，高度 = 1）
- 3D = 三维模拟（半径 = 26，边距 = 6，高度 = 51）
- [几何形状]
- rect = 矩形几何形状
- hex = 六边形几何形状