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Results of colocalisation simulations.

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Figshare2021-09-29 更新2026-04-28 收录
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The columns shown are: scenario: the simulated causal variants in traits 1 and 2, for example A-AB indicates trait 1 has causal variant A and trait 2 has causal variants A and B. nsnps_in_region: Number of SNPs in simulated region (1000, 3000). method: method used for coloc analysis inferred_cv_pair estimated pair of causal variants under test. H0,H1,H2,H3,H4 average posterior support for each hypothesis. This is calculated as the sum of posterior probabilities for each hypothesis / number of simulations run. As some variant pairs are unlikely to be tested (eg the pair AA is unlikely to be tested in the scenario A-B) this is not the expected posterior support given AA is tested. (CSV)
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2021-09-29
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