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IL-2 signaling pathway
IL-2 is a multifunctional cytokine with pleiotropic effects on several cells of the immune system. IL-2 was originally discovered as a T cell growth factor, but it was also found to have actions relat
wikipathways.github.io90
Eicosanoid synthesis
In biochemistry, eicosanoids are signaling molecules made by oxidation of twenty-carbon essential fatty acids, (EFAs). They exert complex control over many bodily systems, mainly in inflammation or im
wikipathways.github.io70
A PGE2-MEF2A axis enables context-dependent control of inflammatory gene expression. A PGE2-MEF2A axis enables context-dependent control of inflammatory gene expression
BMDMs were generated via differentiation of bone marrow cells in culture media containing m-CSF for 7 day. Upon differentiation, BMDMs were left untreated or stimulated with LPS, IFNa, PGE2, LPS+PGE2,
NIAID Data Ecosystem70
GPR68 senses flow and is essential for vascular physiology
GPR68 is an essential flow sensor in arteriolar endothelium, and is a critical signaling component in cardiovascular pathophysiology RNAseq of cells from mesenteric endothelium of mice plus and minus
NIAID Data Ecosystem80
GNAQ pathways in port-wine stain
Port-wine stains are caused by somatic, mosaic mutations in the GNAQ gene. The pathogenic variant is usually a p.R183Q (c.G548A) mutation in guanine nucleotide binding protein alpha subunit q (GNAQ),
wikipathways.github.io70
