knockdown of Histone deacetylase 8 - HDAC8

NIAID Data Ecosystem2026-05-02 收录

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HDAC8 was knocked down in HeLa cells. Peptides were dimethyl labeled and fractionated via SDB-RPS stage tips. After DIA, data was analysed via DIANN

创建时间：

2025-07-02

Elevated expression of histone deacetylase HDAC8 suppresses arginine-proline metabolism in necrotizing enterocolitis. Elevated expression of histone deacetylase HDAC8 suppresses arginine-proline metabolism in necrotizing enterocolitis

To further explore the role of HDAC8 in NEC, we analyzed the signaling pathways that were altered in mice with NEC. We then performed gene expression profiling analysis using data obtained from RNA-se

NIAID Data Ecosystem30

Structural Basis for the Inhibition of Histone Deacetylase 8 (HDAC8), a Key Epigenetic Player in the Blood Fluke Schistosoma mansoni

The treatment of schistosomiasis, a disease caused by blood flukes parasites of the Schistosoma genus, depends on the intensive use of a single drug, praziquantel, which increases the likelihood of th

Figshare2016-01-18 更新10

Crystal structure of human histone deacetylase 8 (HDAC8) I45T mutation complexed with SAHA

Crystal structure of human histone deacetylase 8 (HDAC8) I45T mutation complexed with SAHA Descriptor: 1,2-ETHANEDIOL, Histone deacetylase 8, OCTANEDIOIC ACID HYDROXYAMIDE PHENYLAMIDE, ... Authors: Os

Protein Data Bank Japan2023-10-18 更新20

Structural Basis for the Inhibition of Histone Deacetylase 8 (HDAC8), a Key Epigenetic Player in the Blood Fluke Schistosoma mansoni

NIAID Data Ecosystem30

Characterization of Histone Deacetylase 8 (HDAC8) Selective Inhibition Reveals Specific Active Site Structural and Functional Determinants

Metal-dependent histone deacetylases (HDACs) are key epigenetic regulators that represent promising therapeutic targets for the treatment of numerous human diseases. Yet the currently FDA-approved HDA

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