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Epigenetic reprogramming in relapsed childhood ALL
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2012-06-11
相关数据集
Cell fusion-mediated pluripotent reprogramming triggers ordered changes in chromatin and gene expression across the human inactive X chromosome. Cell fusion-mediated pluripotent reprogramming triggers ordered changes in chromatin and gene expression across the human inactive X chromosome
Erasure of epigenetic memory is required to convert somatic cells towards pluripotency. Reactivation of the inactive X chromosome (Xi) has been used to model epigenetic reprogramming in mouse, but hum
NIAID Data Ecosystem70
Active and Passive Demethylation of Male and Female Pronuclear DNA in the Mammalian Zygote
The epigenomes of mammalian sperm and oocytes, characterized by gamete-specific 5-methylcytosine (5mC) patterns, are reprogrammed during early embryogenesis to establish full developmental potential.
NIAID Data Ecosystem50
Activation-induced deaminase (AID) localizes to the nucleus in brief pulses
Activation-induced deaminase (AID) converts C to U and 5-methyl-C to T. These mutagenic activities are critical to immunoglobulin (Ig) gene diversification and epigenetic reprogramming, but they must
NIAID Data Ecosystem30
Epigenetic reprogramming through KDM6B drives immunofibroblast early commitment and immune properties [CUT&RUN-seq]
TLS are composed of immune cells, including lymphocytes and myeloid cells, lymphatic and blood endothelial cells, and PDPN+ stromal cells with lymphoid stromal cells (LSC) features called immunofibrob
NIAID Data Ecosystem50
Supporting code and data for Tan et al 2024: Pramel15 facilitates zygotic nuclear DNMT1 degradation and DNA demethylation
In mammals, global passive demethylation contributes to epigenetic reprogramming during early embryonic development. At this stage, the majority of DNMT1 protein are excluded from nucleus, which are c
Figshare2024-08-05 更新40
