Predicted p24 epitopes with a high ranking<sup>a</sup> HLA-binding affinity score.
收藏资源简介:
aRanks<10 are considered to be high. bAll peptides listed are predicted to be transported by TAP [36] and cleaved by the proteasome [35]. cThe position of each epitope is given with respect to HXB2-p24 (as in the HIV-1 immunology database). dThe HLA molecule by which the epitope is predicted to be presented. e–indicates that there is no reliable prediction tool for this HLA type. fThe rank of the peptide among all 9-mers from HIV-1 that are predicted to bind the specific HLA molecule (where 1 denotes the best binding epitope) using the SMM method. gThe same predicted rank using a neural network based predictor (NetMHC). hThe HLA supertype to which the HLA molecule belongs according to Sette et al.[38]. iThe HLA supertype to which the HLA molecule belongs according to Lund et al.[59]). jPeptides that have been experimentally confirmed to bind the two-digit HLA type are denoted by +, the four-digit HLA allele by ++, and by HLA molecules from the same supertype as the predicted HLA type by dots.



