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New base editors change C to A in bacteria and C to G in mammalian cells

NIAID Data Ecosystem2026-03-11 收录

基因编辑技术

碱基特异性转换

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA636017 数据链接链接失效反馈

官方服务：

资源简介：

The glycosylase base editor (GBE) approach enables specific C-to-A and C-to-G genomic conversion

应用场景：

创建时间：

2020-05-30

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基因编辑技术

Diffuse intrinsic pontine gliomas (DIPGs) are highly lethal childhood brain tumors. Their unique genetic makeup, pathological heterogeneity, and brainstem location all present challenges to treatment.

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Chromosomal Manipulation by Site-Specific Recombinases and Fluorescent Protein-Based Vectors

基因编辑技术

疾病模型构建

Feasibility of chromosomal manipulation in mammalian cells was first reported 15 years ago. Although this technique is useful for precise understanding of gene regulation in the chromosomal context, a

NIAID Data Ecosystem70

In vitro development of ZFN-injected mouse embryos.

基因编辑技术

胚胎发育研究

In vitro development of ZFN-injected mouse embryos.

Figshare2015-12-02 更新40

prime editing 20230226

基因编辑技术

先导编辑实验

prime editing

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Role of trisomy 21, GATAs mutation and associated mutations in the development of a DS-AMKL model from IPSC: Cut&Tag. Role of trisomy 21, GATAs mutation and associated mutations in the development of a DS-AMKL model from IPSC: Cut&Tag

白血病机制研究

基因编辑技术

Acute megakaryoblastic leukemia of Down syndrome (DS-AMKL) is a model of clonal evolution from a preleukemic transient myeloproliferative disorder requiring both a trisomy 21 (T21) and a GATA1s mutati

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New base editors change C to A in bacteria and C to G in mammalian cells

资源简介：

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