Purpose: To assess effect of PXR functional knockout Overall design: Methods: We obtained expression profiles of cancer cell line HepaRG by RNA-sequencing in various conditions. mRNA profiles of each
Cancer is a systemic disease that includes several noted features, such as pre-metastatic niche formation, cachexia, and immune dysregulation. However, the mechanisms underlying multi-organ failure re
Data are expressed as mean ± SEM (Parentheses indicate the number examined). *P<0.05, **P<0.001, ***P<0.0001 vs. wild-type. BW, body weight; SBP, systolic blood pressure; HR, heart rate; T-Cho, total