Profiling of circulating tumor DNA (ctDNA) in the bloodstream shows promise for non-invasive cancer detection and classification. While chromatin fragmentation features in cell-free DNA (cfDNA) have p
The study goal is to evaluate genetic heterogeneity of circulating tumor cells (CTC) isolated from the blood of patients with metastatic breast cancer. Single CTCs were isolated using EpCAM-independen
Background: Cell free DNA (cfDNA) in plasma has received increasing attention and has been studied in a broad range of clinical conditions implicating inflammation, cancer, and aging. However, few stu