SARS-CoV2 NSP5 in complex with a GC-376 based peptidomimetic PROTAC
收藏Protein Data Bank Japan2024-10-09 更新2026-04-04 收录
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SARS-CoV2 NSP5 in complex with a GC-376 based peptidomimetic PROTAC Descriptor: (phenylmethyl) ~{N}-[(2~{R})-1-[[(~{Z},2~{S})-5-[4-[[1-[2-[(3~{R})-2,6-bis(oxidanylidene)piperidin-3-yl]-6-fluoranyl-1,3-bis(oxidanylidene)isoindol-5-yl]piperidin-4-yl]methyl]piperazin-1-yl]-5-oxidanylidene-1-[(3~{R})-2-oxidanylidenepyrrolidin-3-yl]pent-3-en-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]carbamate, 3C-like proteinase nsp5 Authors: Calderone, V. Deposit date: 2023-03-28 Release date: 2024-01-17 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2 Å) Cite: Development of a GC-376 Based Peptidomimetic PROTAC as a Degrader of 3-Chymotrypsin-like Protease of SARS-CoV-2. Acs Med.Chem.Lett., 15, 2024
创建时间:
2023-03-28



