Whole genome sequencing of WT and diseased LCLs, iPSCs, and HAP1 cells

Whole genome sequencing of 6 presumed healthy LCL samples from 5 unique individuals. All individuals are members of the personal genomes project and are PIGI consented.Whole genome sequencing of 5 iPSC samples of 3 presumed healthy and 2 diseased individuals. All individuals are PIGI consented. iPSC and LCL samples were sourced from Coriell.Whole genome sequencing of 38 HAP1 KO lines, which are nearly-haploid human cell lines derived from a chronic myeloid leukemia patient and readily amenable to CRISPR/Cas9-mediated gene knockout. Of the 38 samples, 6 are WT and 32 have a KO in one of 22 genes.