Understanding how young and old hematopoietic stem cells (HSCs) maintain tissue homeostasis and adapt to intrinsic and extrinsic stress requires defining their metabolic regulation. Here, we quantify
Pluripotent stem cells can be maintained in a continuum of cellular states with distinct features. Exogenous lipid supplements are commonly utilized to shift the balance of global metabolism relieving
Fatty acid beta-oxidation (FAO), the breakdown of lipids, is a metabolic pathway used by various stem cells. FAO levels are generally high during quiescence and downregulated with proliferation. The e
