E-GEOD-7538

NIAID Data Ecosystem2026-05-02 收录

急性髓系白血病转录组学

药物反应基因表达分析

数据链接：

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资源简介：

Transcription profiling of human primary CD34+ acute myelogenous leukemia specimens obtained from 12 patients treated with 7.5 micromolar parthenolide (PTL)

创建时间：

2025-01-24

Transcriptome Analysis of Pediatric Acute Myeloid Leukemia

急性髓系白血病转录组学

肿瘤RNA-seq分析

Purpose: This study aimed to generate a whole transcriptome dataset for children with acute myeloid leukemia Methods: RNA-seq data were generated by deep sequencing using Illumina. The sequence reads

NIAID Data Ecosystem20

81e05ad2-874f-4145-9756-388656a918e5 - samples

急性髓系白血病转录组学

癌症生物标志物

Whole transcriptome RNA-sequencing of purified bone marrow blasts of 136 de novo, treatment naive AML patients. For further details, we refer to the manuscript "The Proteogenomic Landscape of AML" by

NIAID Data Ecosystem20

RNAseq analysis for transcriptomes of DAC treated myeloid malignant cell lines expressing p53-R282W. RNAseq analysis for transcriptomes of DAC treated myeloid malignant cell lines expressing p53-R282W

急性髓系白血病转录组学

表观遗传药物响应

To globally evaluate transcriptome treated by decitabine (DAC) in THP-1 and U937 cells expressing p53-R282W, cells were treated with DMSO or DAC. mRNA was isolated and then subject to deep sequencing,

NIAID Data Ecosystem20

RNA-seq analysis of Men1-/- versus Men1wt MN1-driven AML

急性髓系白血病转录组学

Men1基因功能

Purpose: To characterize transcriptional changes associated with homozygous inactivation of Men1 in MN1 driven AML Methods: In vivo MN1 transformed cells were transduced with Cre-vector to inactivate

NIAID Data Ecosystem20

Effect of Miz1 POZ domain deletion on expression profiles of B and T leukemia cells. Effect of Miz1 POZ domain deletion on expression profiles of B and T leukemia cells

急性髓系白血病转录组学

Miz1POZ结构域功能

Acute lymphoblastic leukemia (ALL) is an aggressive blood cancer mainly affecting children. Relapse rates are high and toxic chemotherapies that block DNA replication and induce DNA damage cause healt

NIAID Data Ecosystem20

E-GEOD-7538

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