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SUDV VLP vaccine protects cynomolgus macaques from lethal infection with SUDV (Boniface isolate).

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NIAID Data Ecosystem2026-03-08 收录
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https://figshare.com/articles/dataset/_SUDV_VLP_vaccine_protects_cynomolgus_macaques_from_lethal_infection_with_SUDV_Boniface_isolate_/1346182
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Macaques were vaccinated with 3 mg of SUDV VLPs (total protein content) along with 100ug of QS-21 at 0 and 6 weeks. Antibody responses were determined using an ELISA to detect IgGs against purified SUDV GPdTM or VP40 in sera drawn immediately prior to challenge. All six macaques were challenged with ∼1000 pfu of SUDV 4 weeks after the final vaccination (week 10). SUDV VLP vaccine protects cynomolgus macaques from lethal infection with SUDV (Boniface isolate).
创建时间:
2015-03-20
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