Expression profiling of mouse livers with inducible over-expression of microRNA Mir483

In this study we generated mice with inducible over-expression of microRNA Mir483, using a transgene inserted at the Rosa26 locus. Whole transcriptome analysis was performed by RNA-seq in livers collected from 15-week old adult mice (over-expressors and controls). We performed RNA-seq analysis in 15-week old mouse livers of adult females with inducible over-expression of microRNA Mir483 (n=6 biological replicates) and littermate controls (n=6 biological replicates)