RIG-I is an intracellular checkpoint that limits CD8+ T-cell antitumour immunity
收藏NIAID Data Ecosystem2026-05-02 收录
官方服务：
资源简介：
Source data of FAC files from mouse and human sample
应用场景：
创建时间：
2024-07-06
相关数据集
ProjecTILs human reference atlas of CD8+ tumor-infiltrating T cells, version 1
ProjecTILs human reference atlas of CD8+ tumor-infiltrating T cells, generated by semi-supervised STACAS integration of scRNA-seq datasets spanning 7 cancer types. The dataset is available as a S
DataCite Commons2025-06-01 更新250
Association between HPK1 expression and T-cell exhaustion. Association between HPK1 expression and T-cell exhaustion
We aimed to investigate the association between HPK1 expression and exhausted status of tumor. Overall design: Bulk RNA-seq was performed on fresh-frozen tissue samples of renal cell carcinoma.
NIAID Data Ecosystem60
Transcriptome analysis of tumor infiltrating NK and T cells in CT26-bearing BALB/C mice
CT26 tumors were implanted subcutaneously into syngeneic BALB/C mice and allowed to grow for 15-25 days. Tumors were collected, mechanically dissociated, and immune cells enriched using Percoll gradie
NIAID Data Ecosystem60
CD39 Identifies Tumor-Reactive CD8 T cells in Patients With Lung Cancer [scRNA]. CD39 Identifies Tumor-Reactive CD8 T cells in Patients With Lung Cancer [scRNA]
We utilized cell surface expression of CD39 to demonstrate that this marker enriches for CD8+ T cells with features of exhaustion, proliferation and tumor reaxtivity. Overall design: We sorted CD3+ T
NIAID Data Ecosystem70
Genes related to immune suppression that are negatively regulated by DMHCA in tumors from NeuT/ATTAC+AP mice.
Genes related to immune suppression that are negatively regulated by DMHCA in tumors from NeuT/ATTAC+AP mice.
NIAID Data Ecosystem60
