Exploiting Temporal Collateral Sensitivity in Tumor Clonal Evolution
收藏官方服务：
资源简介：
Exploiting Temporal Collateral Sensitivity in Tumor Clonal Evolution
应用场景：
创建时间：
2016-04-05
相关数据集
Clonal numbers and variant allele frequencies for driver mutations in 15 WGS metastatic tumors.
Clonal numbers and variant allele frequencies for driver mutations in 15 WGS metastatic tumors.
NIAID Data Ecosystem70
Longitudinal Genome Wide Analysis of Chronic Lymphocytic Leukemia Reveals Complex Evolution of Clonal Architecture at Disease Progression and at the Time of Relapse
Little is known about the extent of intraclonal heterogeneity of CLL tumor cells. We performed longitudinal whole genome analysis in 22 CLL cases with evidence of clinical progression and/or clinical
NIAID Data Ecosystem60
DNA barcoding reveals ongoing immunoediting of clonal cancer populations during metastatic progression and in response to immunotherapy [Bulk RNAseq]. DNA barcoding reveals ongoing immunoediting of clonal cancer populations during metastatic progression and in response to immunotherapy [Bulk RNAseq]
To investigate immunoediting at the primary tumour, we used DNA barcoding combined with NGS to identify individual cancer cells wthin the 4T1 murine model of cancer. We isolated two highly immune evas
NIAID Data Ecosystem50
Multi-color lineage tracing reveals clonal dynamics of squamous carcinoma evolution from initiation to metastasis
Tumor cells are subjected to evolutionary selection pressures during progression from initiation to metastasis. We analyzed the clonal evolution of squamous skin carcinomas induced by DMBA/TPA treatme
NIAID Data Ecosystem70
Genomic heterogeneity and clonal evolution in human gastroesophageal junction cancer revealed by single cell DNA sequencing Raw sequence reads
This study use single cell DNA sequencing to determine genomic variations and clonal evolution related to lymph node metastasis. Multiple Annealing and Looping Based Amplification Cycles (MALBAC) and
NIAID Data Ecosystem60
