Whole Exome Sequencing of Aplastic Anemia Patients Specific to India. Homo sapiens

Aplastic anaemia (AA) is a rare hypocellular bone marrow disease which leads to decrease in reticulin and lack of hematopoiesis. The disease can be acquired or constitutional, with a large number of mutations in the telomerase reverse transcriptase (TERT) gene leading to bone marrow failure. Aplastic anaemia (AA) is a rare hypocellular bone marrow disease which leads to decrease in reticulin and lack of hematopoiesis. The disease can be acquired or constitutional, with a large number of mutations in the telomerase reverse transcriptase (TERT) gene leading to bone marrow failure.