Manipulating the regioselectivity of phenylalanine aminomutase: new insights into the reaction mechanism of MIO-dependent enzymes from structure-guided directed evolution
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Manipulating the regioselectivity of phenylalanine aminomutase: new insights into the reaction mechanism of MIO-dependent enzymes from structure-guided directed evolution Descriptor: BETA-MERCAPTOETHANOL, FORMIC ACID, GLYCEROL, ... Authors: Wu, B, Szymanski, W, Wybenga, G.G, Heberling, M.M, Bartsch, S, Wildeman, S, Poelarends, G.J, Feringa, B.L, Dijkstra, B.W, Janssen, D.B. Deposit date: 2011-05-13 Release date: 2011-11-09 Last modified: 2025-10-01 Method: X-RAY DIFFRACTION (2.18 Å) Cite: Mechanism-Inspired Engineering of Phenylalanine Aminomutase for Enhanced Beta-Regioselective Asymmetric Amination of Cinnamates. Angew.Chem.Int.Ed.Engl., 51, 2012
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2011-05-13
