Despite extensive research, our understanding of the rules according to which cis-regulatory sequences are converted into gene expression is limited We devised a method for obtaining parallel, highly
In mammals, fine motor control is essential for skilled behavior, and is subserved by specialized subdivisions of the primary motor cortex (M1) and other components of the brain's motor circuitry. We
The critical process in development, bifurcation of cellular fates, requires epigenetic H3K27me3 marks propagated by PRC2 complex. However, the precise chromatin loci of functional H3K27me3 marks are
A protocol for performing the 4C library and the analysis in mice macrophages. We used the ChIP-seq data to mark the DNA element regions (Silencer) and used the 4C-seq technique to investigate all the
