Association between IL23R p.Arg381Gln (rs11209026) genotype and CD disease characteristics in the subcohort of the Munich IBD center (n = 452) for which detailed phenotypic data based on the Montreal classification [40] were available.
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For each variable, the number of patients included is given.*In this subgroup, there were no AA homozygous carriers for the genotype-phenotype analysis available.1Disease behaviour was defined according to the Montreal classification [40]. A stricturing disease phenotype was defined as presence of stenosis without penetrating disease. The diagnosis of stenosis was made surgically, endoscopically, or radiologically (using MRI enteroclysis).2Immunosuppressive agents included azathioprine, 6-mercaptopurine, 6-thioguanin, methotrexate, and/or infliximab.3Only surgery related to CD-specific problems (e.g. fistulectomy, colectomy, ileostomy) was included.
创建时间:
2015-12-02



