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Supplementary Table S5 from ER-851, a Novel Selective Inhibitor of AXL, Overcomes Resistance to Antimitotic Drugs

NIAID Data Ecosystem2026-04-30 收录

肿瘤耐药性逆转

AXL抑制剂开发

数据链接：

https://figshare.com/articles/dataset/Supplementary_Table_S5_from_ER-851_a_Novel_Selective_Inhibitor_of_AXL_Overcomes_Resistance_to_Antimitotic_Drugs/30734137 数据链接链接失效反馈

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资源简介：

Supplementary Data Table S5

应用场景：

创建时间：

2023-01-03

肿瘤耐药性逆转

药物作用机制

Ovarian tumor cells (OVCA-8 and its reistant variant) were treated with NCX4040 for different times in 10% FBS and RNA was isolated by triazol method OVCAR and NCI/ADR-RES cells were treated with NCX

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CDK4/6 inhibitors reverse primary resistance to anti-PD-1 therapy in LKB1-deficient lung adenocarcinoma. CDK4/6 inhibitors reverse primary resistance to anti-PD-1 therapy in LKB1-deficient lung adenocarcinoma

肿瘤免疫治疗

肿瘤耐药性逆转

LKB1 deficiency in lung adenocarcinoma (LUAD) leads to primary resistance to immune checkpoint inhibitors. However, the underlying molecular mechanism remains unclear. Here, we showed that LKB1 defici

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Design of Novel 2‑Phenylquinazolin-4-amines as Selective CYP1B1 Inhibitors for Overcoming Paclitaxel Resistance in A549 Cells

CYP1B1

肿瘤耐药性逆转

Cytochrome P450 1B1 (CYP1B1) contributes to the metabolic inactivation of chemotherapeutics when overexpressed in tumor cells. Selective inhibition of CYP1B1 holds promise for reversing drug resistanc

Figshare40

Ginseng polysaccharides circumvent acquired resistance to anti-PD-1 immunotherapy in patients with non-small cell lung cancer

肿瘤耐药性逆转

中药辅助免疫疗法

Ginseng polysaccharides enhance the therapeutic efficacy of anti-programmed cell death 1 (PD-1) monoclonal antibody (mAb) in combating tumors. Furthermore, ginseng polysaccharides can function as an a

NIAID Data Ecosystem70

Supplementary Table S3 from ER-851, a Novel Selective Inhibitor of AXL, Overcomes Resistance to Antimitotic Drugs

肿瘤耐药性逆转

靶向药物开发

Supplementary Table S3

Figshare2023-01-03 更新50