Data from: Tissue-specific mutagenesis from endogenous guanine damage is suppressed by PolK and DNA repair
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https://datadryad.org/dataset/doi:10.5061/dryad.r4xgxd2sp
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资源简介：
We report here LC-MS data using targeted adductomics and biochemical
analyses to identify endogenous N2-dG lesions requiring Polk-mediated
bypass, and untargeted adductomics to reveal new guanine lesions that
engage NER. These findings uncover the nature of endogenous DNA damage and
the coordinated roles of repair and tolerance pathways that limit
mutagenesis in tissues.
提供机构：
Dryad
创建时间：
2025-11-19
